|
|
13-dihydrodaunorubicin + NADPH + H+ + O2 <=> daunorubicin + NADP+ + H2O
|
1.14.13.181
13-deoxydaunorubicin hydroxylase
|
–
|
BMK
|
| |
BRENDA:
BR50585
KEGG:
R06689
MetaCyc:
RXN-14830
|
|
|
|
S-adenosyl-L-methionine + carminomycin <=> daunorubicin + S-adenosyl-L-homocysteine + H+
|
2.1.1.292
carminomycin 4-O-methyltransferase
|
–
|
BMK
|
| |
BRENDA:
BR50635
KEGG:
R06693
MetaCyc:
RXN-14828
|
|
|
|
daunorubicin + NADPH + H+ + O2 <=> doxorubicin + NADP+ + H2O
|
1.14.13.181
13-deoxydaunorubicin hydroxylase
|
–
|
MK
|
| |
BRENDA:
BS421946
KEGG:
R06690
MetaCyc:
RXN-14855
|
|
|
|
daunorubicin + NADPH + H+ <=> 13-dihydrodaunorubicin + NADP+
|
1.1.1.149
20alpha-hydroxysteroid dehydrogenase
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.239
3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
|
–
–
–
|
|
| |
BRENDA:
BS383121
SABIO-RK:
12037
|
|
|
|
daunorubicin <=> 13-dihydrodaunorubicin
|
not assigned
|
–
|
K
|
| |
KEGG:
R06694
|
|
|
|
2 S-adenosyl-L-methionine + daunorubicin <=> 2 S-adenosyl-L-homocysteine + O-methyldaunorubicin
|
2.1.1.B75
|
–
|
|
| |
BRENDA:
BS454841
|
|
|
|
glutathione + daunorubicin <=> Cys-Gly + 5-L-glutamyl-daunomycin
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
| |
BRENDA:
BS321688
|
|
|
|
daunorubicin + NADP+ <=> 7-deoxydaunomycinone + NADPH
|
1.18.1.2
ferredoxin---NADP+ reductase
|
–
|
|
| |
BRENDA:
BS186827
|
|
|
|
daunorubicin + ATP + H2O <=> daunorubicin + ADP + phosphate
|
7.5.2.6
ABC-type lipid A-core oligosaccharide transporter
7.6.2.2
ABC-type xenobiotic transporter
|
–
–
|
|
| |
BRENDA:
BS141500
|
|
